Primjena podatkovne znanosti u farmakoekonomskoj analizi potrošnje lijekova u Republici Hrvatskoj

master's thesis

• Title (english): Application of data science in a pharmacoeconomic analysis of drug consumption in Republic of Croatia
• Author: Ante Raguž
• Mentor: Mirjana Pejić Bach (mentor)
• Committee member: Božidar Jaković (predsjednik povjerenstva)
• Committee member: Nikola Vlahović (član povjerenstva)
• Granter: University of Zagreb; Faculty of Economics and Business; (Department of Informatics); Zagreb
• Defense date and country: 2024-09-24, Croatia
• Scientific / art field, discipline and subdiscipline: SOCIAL SCIENCES; Economics; Business Informatics

Abstract

Hrvatska Agencija za lijekove i medicinske proizvode, kao jedino ovlašteno tijelo u Republici Hrvatskoj, svake godine objavljuje potrošnju lijekova za prethodnu godinu. Izvještaji obuhvaćaju potrošnju po definiranim dnevnim dozama i financijskom utrošku poštujući farmakoekonomske principe. Farmakoekonomika je ekonomska disciplina koja utvrđuje troškove lijekova kroz vrijeme te uspoređuje stvarne učinke farmaceutskih proizvoda i zdravstvenih programa.
U ovom istraživanju analizirana je potrošnja lijekova u razdoblju prije i za vrijeme pandemije COVID-19 (2019. – 2022.) s ciljem utvrđivanja je li pandemija značajno utjecala na potrošnju lijekova u zemlji. Podaci su obrađeni korištenjem metoda podatkovne analize uz primjenu programa Weka. Rezultati pokazuju da u izvanbolničkoj potrošnji lijekova na razini cijele Hrvatske nije bilo značajnih oscilacija u dnevnim dozama te se bilježi trend blagog rasta za sve skupine lijekova. Nasuprot tome, zabilježen je značajan financijski rast, najviše u skupinama J (potaknut cjepivima za COVID-19) te posebno skupim lijekovima iz skupine L (lijekovi za rijetke i teške bolesti). Povećanje potrošnje lijekova može se pripisati starenju stanovništva, stalnom razvoju farmaceutske industrije (posebno generičkih i inovativnih pametnih lijekova) te sklonosti ljudi ka sve većem korištenju farmaceutskih pripravaka. Međutim, porast samih cijena lijekova u ovom razdoblju je najviše rezultat opće inflacije u globalnoj ekonomiji indirektno potaknutoj COVID-19 pandemijom i ratnim zbivanjima u svijetu. Sveukupno, rezultati istraživanja ukazuju na to da pandemija COVID-19 nije značajno utjecala na izvanbolničku i bolničku potrošnju lijekova pojedinačnih terapijskih skupina u Republici Hrvatskoj. Hrvatski zdravstveni sustav izdržao je pritisak pandemije te je paralelno održao funkciju liječenja ostalih zdravstvenih potreba stanovništva.

Abstract (english)

The Croatian Agency for Medicines and Medical Products, as the only authorized body in Republic of Croatia, annually publishes a report on expenditure of medicines for the previous year. Reports include consumption according to defined daily doses and financial expenditure respecting pharmacoeconomic principles. Pharmacoeconomics is an economic discipline that determines the costs of drugs over time and compares the actual effects of pharmaceutical products and health programs.
This research analysed medicine expenditure in the period before and during the COVID-19 pandemic (2019–2022) with the aim of determining whether the pandemic had a significant impact on drug expenditure in the country. Data was processed using data analysis methods alongside application of the Weka program. Results show that for out-of-hospital consumption of medicines, there were no significant oscillations in daily doses, and a slight growth trend was noted for all groups of medicines. In contrast, significant financial growth was recorded, mostly in group J (stimulated by vaccines for COVID-19) and particularly expensive drugs from group L (drugs for rare and serious diseases). The increase in drug consumption can be attributed to general aging of the population, constant development of the pharmaceutical industry (especially generic and innovative smart drugs) and tendency to use pharmaceuticals more often. However, the increase in drug prices alone is mostly the result of general inflation in the global economy indirectly stimulated by the COVID-19 pandemic and recent war events in the world. Overall, the results of this research indicate that COVID-19 pandemic did not significantly affect the outpatient and hospital consumption of drugs for individual therapeutic groups in the Republic of Croatia. The Croatian health system withstood the pressure of the pandemic and, in parallel, maintained the function of treating other population health needs.

• Keywords: potrošnja lijekova; farmakoekonomika; klaster analiza; baze podataka; COVID-19
• Keywords (english): drug expenditure; pharmacoeconomics; cluster analysis; databases; COVID-19
• Language: croatian
• URN:NBN: urn:nbn:hr:148:729829
• Study programme: Title: Business economics; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: sveučilišni magistar ekonomije/sveučilišna magistra ekonomije (sveučilišni magistar ekonomije/sveučilišna magistra ekonomije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Access restricted to authenticated users
• Created on: 2024-09-24 13:36:36